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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2Q2
All Species:
31.52
Human Site:
Y157
Identified Species:
57.78
UniProt:
Q8WVN8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVN8
NP_001138807.1
375
42818
Y157
D
I
E
D
L
D
H
Y
E
M
K
E
E
E
P
Chimpanzee
Pan troglodytes
XP_001145531
375
42784
Y157
D
I
E
D
L
D
H
Y
E
M
K
E
E
E
P
Rhesus Macaque
Macaca mulatta
XP_001111833
440
48588
Y222
D
T
E
D
L
D
H
Y
E
M
K
E
E
E
P
Dog
Lupus familis
XP_535548
453
50033
Y235
D
I
E
D
L
D
H
Y
E
M
K
E
E
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Z8
378
42917
Y160
D
I
E
D
L
D
H
Y
E
M
K
E
E
E
P
Rat
Rattus norvegicus
XP_001072896
377
42801
Y159
D
I
E
D
L
D
H
Y
E
M
K
E
E
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507003
302
34322
K96
E
E
P
V
D
G
K
K
S
E
D
E
G
I
E
Chicken
Gallus gallus
XP_413740
404
45007
Y186
D
I
E
D
L
D
H
Y
D
M
K
E
E
E
P
Frog
Xenopus laevis
NP_001083463
368
41875
Y150
D
I
E
D
L
D
H
Y
D
M
K
E
E
E
P
Zebra Danio
Brachydanio rerio
XP_002665470
372
42539
H154
G
E
D
I
D
L
E
H
Y
E
M
K
E
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM35
306
33651
V100
G
A
A
K
N
A
V
V
R
M
A
A
E
Q
A
Honey Bee
Apis mellifera
XP_393110
382
42857
L158
D
A
E
E
D
L
H
L
D
M
D
E
G
D
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786851
341
38680
N135
P
S
K
N
E
K
D
N
D
E
K
E
I
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
65.9
72.6
N.A.
94.9
95.2
N.A.
71.7
74.2
86.4
82.9
N.A.
29.8
56.2
N.A.
53
Protein Similarity:
100
99.7
73.4
76.5
N.A.
96.3
96.5
N.A.
76.2
79.6
92
90.1
N.A.
49.3
75.6
N.A.
73.6
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
6.6
93.3
93.3
20
N.A.
13.3
33.3
N.A.
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
13.3
100
100
40
N.A.
20
53.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
0
8
0
0
0
0
8
8
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
8
62
24
62
8
0
31
0
16
0
0
16
0
% D
% Glu:
8
16
70
8
8
0
8
0
47
24
0
85
77
70
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
0
8
0
0
0
0
0
0
16
0
0
% G
% His:
0
0
0
0
0
0
70
8
0
0
0
0
0
0
0
% H
% Ile:
0
54
0
8
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
8
8
0
8
8
8
0
0
70
8
0
0
0
% K
% Leu:
0
0
0
0
62
16
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
77
8
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
70
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _